null

SMILES: F[C@H]1CCN(C1)C(=O)C1CNCc2nn(Cc3ccc(F)c(c3)C(F)(F)F)c(=O)n12

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 554502   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prolyl endopeptidase (Homo sapiens (Human))	BDBM554502 ((5RS)-5-{[(3S)-3-Fluoropyrrolidin-1-yl]carbonyl}-2...) Show SMILES F[C@H]1CCN(C1)C(=O)C1CNCc2nn(Cc3ccc(F)c(c3)C(F)(F)F)c(=O)n12 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.670	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description To recombinant full-length human prolyl endopeptidase (PREP, R&D-Systems, 4308-SE; final concentration, for example, 0.4 nM, volume: 25 al) in reacti...				Citation and Details BindingDB Entry DOI: 10.7270/Q28P63RC
					More data for this Ligand-Target Pair
Prolyl endopeptidase (Homo sapiens (Human))	BDBM554502 ((5RS)-5-{[(3S)-3-Fluoropyrrolidin-1-yl]carbonyl}-2...) Show SMILES F[C@H]1CCN(C1)C(=O)C1CNCc2nn(Cc3ccc(F)c(c3)C(F)(F)F)c(=O)n12 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	455	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description To recombinant full-length human prolyl endopeptidase (PREP, R&D-Systems, 4308-SE; final concentration, for example, 0.4 nM, volume: 25 al) in reacti...				Citation and Details BindingDB Entry DOI: 10.7270/Q28P63RC
					More data for this Ligand-Target Pair
Prolyl endopeptidase (Homo sapiens (Human))	BDBM554502 ((5RS)-5-{[(3S)-3-Fluoropyrrolidin-1-yl]carbonyl}-2...) Show SMILES F[C@H]1CCN(C1)C(=O)C1CNCc2nn(Cc3ccc(F)c(c3)C(F)(F)F)c(=O)n12 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description To recombinant full-length human prolyl endopeptidase (PREP, R&D-Systems, 4308-SE; final concentration, for example, 0.4 nM, volume: 25 al) in reacti...				Citation and Details BindingDB Entry DOI: 10.7270/Q28P63RC
					More data for this Ligand-Target Pair