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SMILES: Cc1ccc(Cn2nc3CN(CC(C(=O)N4CCCC4)n3c2=O)C(=O)Nc2ccc(cc2)C(F)(F)F)cc1

InChI Key:

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 554520   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Prolyl endopeptidase


(Homo sapiens (Human))		BDBM554520
PNG
((5RS)-2-(4-Methylbenzyl)-3-oxo-5-(pyrrolidin-1-ylc...)
Show SMILES Cc1ccc(Cn2nc3CN(CC(C(=O)N4CCCC4)n3c2=O)C(=O)Nc2ccc(cc2)C(F)(F)F)cc1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 0.660n/an/an/an/an/an/a


TBA

Assay Description
To recombinant full-length human prolyl endopeptidase (PREP, R&D-Systems, 4308-SE; final concentration, for example, 0.4 nM, volume: 25 al) in reacti...

Citation and Details

BindingDB Entry DOI: 10.7270/Q28P63RC
More data for this
Ligand-Target Pair