null

SMILES: COC(C)(C)COc1cnccc1-c1[nH]c2CCNC(=O)c2c1Nc1cccc(F)c1O

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 555130   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor [669-770,'SVD',771-1210] (Homo sapiens (Human))	BDBM555130 (3-[(3-fluoro-2-hydroxyphenyl)amino]-2-[3-(2-methox...) Show SMILES COC(C)(C)COc1cnccc1-c1[nH]c2CCNC(=O)c2c1Nc1cccc(F)c1O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.634	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Exon 20-Mutant-EGFR(V769_D770insASV): For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into either a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2H70K0Q
					More data for this Ligand-Target Pair
Epidermal growth factor receptor [669-770,'SVD',771-1210] (Homo sapiens (Human))	BDBM555130 (3-[(3-fluoro-2-hydroxyphenyl)amino]-2-[3-(2-methox...) Show SMILES COC(C)(C)COc1cnccc1-c1[nH]c2CCNC(=O)c2c1Nc1cccc(F)c1O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.541	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Exon 20-Mutant-EGFR(D770_N771insSVD): For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into either a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2H70K0Q
					More data for this Ligand-Target Pair