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SMILES: Cn1ccc(cc1=O)-c1ccc(cc1)C1CC1NCC1CCN(CCCc2ccc(cc2)C(=O)NO)CC1

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 556404   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 6 (Homo sapiens (Human))	BDBM556404 (N-hydroxy-4-(3-(4-(((2-(4-(1-methyl-2-oxo-1,2-dihy...) Show SMILES Cn1ccc(cc1=O)-c1ccc(cc1)C1CC1NCC1CCN(CCCc2ccc(cc2)C(=O)NO)CC1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	46	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Histone deacetylase assay was done as per manufacturer's instructions. Briefly, assay buffer, 200 uM HDAC substrate (fluorogenic HDAC acetylated ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NS0Z4T
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM556404 (N-hydroxy-4-(3-(4-(((2-(4-(1-methyl-2-oxo-1,2-dihy...) Show SMILES Cn1ccc(cc1=O)-c1ccc(cc1)C1CC1NCC1CCN(CCCc2ccc(cc2)C(=O)NO)CC1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description LSD1 enzyme was produced in house. Tranylcypromine (TCP), LSD1 inhibitor was procured from Selleckchem. LSD1 enzyme, TCP and Biotinylated peptide sub...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NS0Z4T
					More data for this Ligand-Target Pair