null
SMILES: Nc1ccccc1NC(=O)c1ccc(CCCN2CCC(CNC3CC3c3ccc(cc3)C(=O)N3CCCCC3)CC2)cc1
InChI Key:
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Lysine-specific histone demethylase 1A (Homo sapiens (Human)) | BDBM556495 (N-(2-aminophenyl)-4-(3-(4-(((2-(4-(piperidine-1-ca...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 21 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description LSD1 enzyme was produced in house. Tranylcypromine (TCP), LSD1 inhibitor was procured from Selleckchem. LSD1 enzyme, TCP and Biotinylated peptide sub... | Citation and Details BindingDB Entry DOI: 10.7270/Q2NS0Z4T | |||||||||||
More data for this Ligand-Target Pair |