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SMILES: Cc1cnc([nH]1)-c1cc(ccn1)-c1cncc(c1)S(=O)(=O)N[C@H]1CC[C@](C)(O)CC1

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 557245   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM557245 (US11352340, Example 298) Show SMILES Cc1cnc([nH]1)-c1cc(ccn1)-c1cncc(c1)S(=O)(=O)N[C@H]1CC[C@](C)(O)CC1 |r,wU:22.24,25.28,wD:25.29,(-.8,7.04,;-.03,5.7,;-.93,4.46,;-.03,3.21,;1.44,3.69,;1.44,5.23,;2.77,2.92,;2.77,1.38,;4.1,.61,;5.44,1.38,;5.44,2.92,;4.1,3.69,;4.1,-.93,;5.44,-1.7,;5.44,-3.24,;4.1,-4.01,;2.77,-3.24,;2.77,-1.7,;1.44,-4.01,;.67,-5.34,;2.21,-5.34,;.1,-3.24,;-1.23,-4.01,;-1.23,-5.55,;-2.56,-6.32,;-3.9,-5.55,;-5.44,-5.55,;-4.3,-7.04,;-3.9,-4.01,;-2.56,-3.24,)| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase reaction was conducted in polystyrene 384-well Greiner Bio-one white plate from Thermo Fisher Scientific in a final volume of 25 μL. ...				Citation and Details BindingDB Entry DOI: 10.7270/Q24T6NKW
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM557245 (US11352340, Example 298) Show SMILES Cc1cnc([nH]1)-c1cc(ccn1)-c1cncc(c1)S(=O)(=O)N[C@H]1CC[C@](C)(O)CC1 |r,wU:22.24,25.28,wD:25.29,(-.8,7.04,;-.03,5.7,;-.93,4.46,;-.03,3.21,;1.44,3.69,;1.44,5.23,;2.77,2.92,;2.77,1.38,;4.1,.61,;5.44,1.38,;5.44,2.92,;4.1,3.69,;4.1,-.93,;5.44,-1.7,;5.44,-3.24,;4.1,-4.01,;2.77,-3.24,;2.77,-1.7,;1.44,-4.01,;.67,-5.34,;2.21,-5.34,;.1,-3.24,;-1.23,-4.01,;-1.23,-5.55,;-2.56,-6.32,;-3.9,-5.55,;-5.44,-5.55,;-4.3,-7.04,;-3.9,-4.01,;-2.56,-3.24,)| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase reaction was conducted in polystyrene 384-well Greiner Bio-one white plate from Thermo Fisher Scientific in a final volume of 25 μL. ...				Citation and Details BindingDB Entry DOI: 10.7270/Q24T6NKW
					More data for this Ligand-Target Pair