null
SMILES: Fc1cc(ccc1-c1cccc(OC(F)(F)F)c1)C(=O)N1CCN(CC1)c1nc2ccccc2c(=O)[nH]1
InChI Key:
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Monoglyceride lipase (Homo sapiens (Human)) | BDBM561321 (US11390610, Example 150) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 42 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Compounds of the present invention are MAGL inhibitors. Thus, in one aspect, the present invention provides the use of compounds of Formula (I) or a ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2W0994M | |||||||||||
More data for this Ligand-Target Pair |