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SMILES: CCn1nccc1-c1c(nc(N)c2nn(Cc3cccc(C)n3)cc12)-c1cccc(c1)C#N

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 561397   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Adenosine receptor A2a (Homo sapiens (Human))	BDBM561397 (3-(7-amino-4-(1-ethyl-1H-pyrazol-5-yl)-2-((6-methy...) Show SMILES CCn1nccc1-c1c(nc(N)c2nn(Cc3cccc(C)n3)cc12)-c1cccc(c1)C#N |(2.92,3.35,;1.78,2.32,;.32,2.8,;-.16,4.26,;-1.7,4.26,;-2.18,2.8,;-.93,1.9,;-.93,.36,;-2.26,-.41,;-2.26,-1.95,;-.93,-2.72,;-.93,-4.26,;.4,-1.95,;1.87,-2.43,;2.77,-1.18,;4.31,-1.18,;5.08,.15,;4.31,1.48,;5.08,2.82,;6.62,2.82,;7.39,1.48,;8.93,1.48,;6.62,.15,;1.87,.06,;.4,-.41,;-3.6,.36,;-3.6,1.9,;-4.93,2.67,;-6.27,1.9,;-6.27,.36,;-4.93,-.41,;-7.6,-.41,;-8.93,-1.18,)| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Stably transfected HEK-293 cells expressing the human adenosine A2A receptor (Perkin Elmer) are maintained in MEM culture medium with 10% FBS and 400...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MK6H4B
					More data for this Ligand-Target Pair
Adenosine receptor A2b (Homo sapiens (Human))	BDBM561397 (3-(7-amino-4-(1-ethyl-1H-pyrazol-5-yl)-2-((6-methy...) Show SMILES CCn1nccc1-c1c(nc(N)c2nn(Cc3cccc(C)n3)cc12)-c1cccc(c1)C#N |(2.92,3.35,;1.78,2.32,;.32,2.8,;-.16,4.26,;-1.7,4.26,;-2.18,2.8,;-.93,1.9,;-.93,.36,;-2.26,-.41,;-2.26,-1.95,;-.93,-2.72,;-.93,-4.26,;.4,-1.95,;1.87,-2.43,;2.77,-1.18,;4.31,-1.18,;5.08,.15,;4.31,1.48,;5.08,2.82,;6.62,2.82,;7.39,1.48,;8.93,1.48,;6.62,.15,;1.87,.06,;.4,-.41,;-3.6,.36,;-3.6,1.9,;-4.93,2.67,;-6.27,1.9,;-6.27,.36,;-4.93,-.41,;-7.6,-.41,;-8.93,-1.18,)| Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	55	n/a	n/a	n/a	n/a
TBA					Assay Description Stably transfected HEK-293 cells expressing the human adenosine A2B receptor (Perkin Elmer) were maintained in MEM culture medium with 10% FBS and 10...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MK6H4B
					More data for this Ligand-Target Pair