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SMILES: Cc1ncoc1-c1c(nc(N)c2nn(CCc3ccccn3)nc12)-c1cccc(c1)C#N

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 561434   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Adenosine receptor A2a (Homo sapiens (Human))	BDBM561434 (3-(4-amino-7-(4-methyloxazol-5-yl)-2-(2-(pyridin-2...) Show SMILES Cc1ncoc1-c1c(nc(N)c2nn(CCc3ccccn3)nc12)-c1cccc(c1)C#N |(1.47,2.32,;.01,2.8,;-.47,4.26,;-2.01,4.26,;-2.48,2.8,;-1.24,1.9,;-1.24,.36,;-2.57,-.41,;-2.57,-1.95,;-1.24,-2.72,;-1.24,-4.26,;.1,-1.95,;1.56,-2.43,;2.47,-1.18,;4.01,-1.18,;4.78,.15,;6.26,.55,;7.35,-.54,;8.84,-.14,;9.24,1.34,;8.15,2.43,;6.66,2.03,;1.56,.06,;.1,-.41,;-3.9,.36,;-3.9,1.9,;-5.24,2.67,;-6.57,1.9,;-6.57,.36,;-5.24,-.41,;-7.91,-.41,;-9.24,-1.18,)| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Stably transfected HEK-293 cells expressing the human adenosine A2A receptor (Perkin Elmer) are maintained in MEM culture medium with 10% FBS and 400...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MK6H4B
					More data for this Ligand-Target Pair
Adenosine receptor A2b (Homo sapiens (Human))	BDBM561434 (3-(4-amino-7-(4-methyloxazol-5-yl)-2-(2-(pyridin-2...) Show SMILES Cc1ncoc1-c1c(nc(N)c2nn(CCc3ccccn3)nc12)-c1cccc(c1)C#N |(1.47,2.32,;.01,2.8,;-.47,4.26,;-2.01,4.26,;-2.48,2.8,;-1.24,1.9,;-1.24,.36,;-2.57,-.41,;-2.57,-1.95,;-1.24,-2.72,;-1.24,-4.26,;.1,-1.95,;1.56,-2.43,;2.47,-1.18,;4.01,-1.18,;4.78,.15,;6.26,.55,;7.35,-.54,;8.84,-.14,;9.24,1.34,;8.15,2.43,;6.66,2.03,;1.56,.06,;.1,-.41,;-3.9,.36,;-3.9,1.9,;-5.24,2.67,;-6.57,1.9,;-6.57,.36,;-5.24,-.41,;-7.91,-.41,;-9.24,-1.18,)| Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	55	n/a	n/a	n/a	n/a
TBA					Assay Description Stably transfected HEK-293 cells expressing the human adenosine A2B receptor (Perkin Elmer) were maintained in MEM culture medium with 10% FBS and 10...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MK6H4B
					More data for this Ligand-Target Pair