BDBM5638 3-(3-Methylthien-2-yl)-5-(acetamido)indeno[1,2-c]pyrazol-4-one::Indenopyrazole 13u::N-[3-(3-methylthiophen-2-yl)-4-oxo-2H,4H-indeno[1,2-c]pyrazol-5-yl]acetamide

SMILES: CC(=O)Nc1cccc2-c3n[nH]c(-c4sccc4C)c3C(=O)c12

InChI Key: InChIKey=FGMFUNRHGWNTBG-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 5638   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
CDK2/CycE (Homo sapiens (Human))	BDBM5638 (3-(3-Methylthien-2-yl)-5-(acetamido)indeno[1,2-c]p...) Show SMILES CC(=O)Nc1cccc2-c3n[nH]c(-c4sccc4C)c3C(=O)c12 Show InChI InChI=1S/C17H13N3O2S/c1-8-6-7-23-17(8)15-13-14(19-20-15)10-4-3-5-11(18-9(2)21)12(10)16(13)22/h3-7H,1-2H3,(H,18,21)(H,19,20)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	260	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description The enzyme was assayed with substrate GST-Rb in the presence of 50 uM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...				J Med Chem 45: 5233-48 (2002) Article DOI: 10.1021/jm0201722 BindingDB Entry DOI: 10.7270/Q2MG7MQJ
					More data for this Ligand-Target Pair
Cyclin-Dependent Kinase 4 (CDK4) (Homo sapiens (Human))	BDBM5638 (3-(3-Methylthien-2-yl)-5-(acetamido)indeno[1,2-c]p...) Show SMILES CC(=O)Nc1cccc2-c3n[nH]c(-c4sccc4C)c3C(=O)c12 Show InChI InChI=1S/C17H13N3O2S/c1-8-6-7-23-17(8)15-13-14(19-20-15)10-4-3-5-11(18-9(2)21)12(10)16(13)22/h3-7H,1-2H3,(H,18,21)(H,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>3.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description The enzyme was assayed with substrate GST-Rb in the presence of 50 uM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...				J Med Chem 45: 5233-48 (2002) Article DOI: 10.1021/jm0201722 BindingDB Entry DOI: 10.7270/Q2MG7MQJ
					More data for this Ligand-Target Pair