null

SMILES: CCc1[nH]nc2-c3cccc(NC(N)=O)c3C(=O)c12

InChI Key: InChIKey=FEKJNYQHDFBPEY-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 5641   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-dependent kinase 2/G1/S-specific cyclin-E1 (Homo sapiens (Human))	BDBM5641 (3-Ethyl-5-(carbamoylamino)indeno[1,2-c]pyrazol-4-o...) Show SMILES CCc1[nH]nc2-c3cccc(NC(N)=O)c3C(=O)c12 Show InChI InChI=1S/C13H12N4O2/c1-2-7-10-11(17-16-7)6-4-3-5-8(15-13(14)19)9(6)12(10)18/h3-5H,2H2,1H3,(H,16,17)(H3,14,15,19)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description The enzyme was assayed with substrate GST-Rb in the presence of 50 uM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...				J Med Chem 45: 5233-48 (2002) Article DOI: 10.1021/jm0201722 BindingDB Entry DOI: 10.7270/Q2MG7MQJ
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 4/G1/S-specific cyclin-D1 (Homo sapiens (Human))	BDBM5641 (3-Ethyl-5-(carbamoylamino)indeno[1,2-c]pyrazol-4-o...) Show SMILES CCc1[nH]nc2-c3cccc(NC(N)=O)c3C(=O)c12 Show InChI InChI=1S/C13H12N4O2/c1-2-7-10-11(17-16-7)6-4-3-5-8(15-13(14)19)9(6)12(10)18/h3-5H,2H2,1H3,(H,16,17)(H3,14,15,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description The enzyme was assayed with substrate GST-Rb in the presence of 50 uM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...				J Med Chem 45: 5233-48 (2002) Article DOI: 10.1021/jm0201722 BindingDB Entry DOI: 10.7270/Q2MG7MQJ
					More data for this Ligand-Target Pair