null
SMILES: Nc1nccc2n(Cc3cc(ncc3N3CCC[C@@H](C3)c3ccn(n3)C(F)F)-c3ccc(F)cc3)cnc12
InChI Key:
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Histone-lysine N-methyltransferase NSD2 (Homo sapiens (Human)) | BDBM568077 (US11420970, Example 279) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 5.5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description This assay employed LC-MS/MS technology to monitor the SAH production from the NSD2 enzymatic reaction. The enzymatic reaction was performed in white... | Citation and Details BindingDB Entry DOI: 10.7270/Q27084N0 | |||||||||||
More data for this Ligand-Target Pair |