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Enter Data

null

SMILES: C=CC(=O)Nc1ccc(cc1)C(=O)N1CC[C@H](C1)Nc1ncc2ccc(cc2n1)C#N

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 572072
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Cyclin-K/Cyclin-dependent kinase 12 (Homo sapiens (Human))	BDBM572072 ((R)-N-(4-(3-((7-cyanoquinazolin-2- yl)amino)pyrrol...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description A radiometric protein kinase assay (33PanQinase� Activity Assay) was used for measuring the kinase activity of the three protein kinases. All kinase ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2CF9TBB
TBA					More data for this Ligand-Target Pair
Cyclin-K/Cyclin-dependent kinase 12 (Homo sapiens (Human))	BDBM572072 ((R)-N-(4-(3-((7-cyanoquinazolin-2- yl)amino)pyrrol...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description A radiometric protein kinase assay (33PanQinase� Activity Assay) was used for measuring the kinase activity of the protein kinase. All kinase assays ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2CF9TBB
TBA					More data for this Ligand-Target Pair
CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7 (Homo sapiens (Human))	BDBM572072 ((R)-N-(4-(3-((7-cyanoquinazolin-2- yl)amino)pyrrol...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description A radiometric protein kinase assay (33PanQinase� Activity Assay) was used for measuring the kinase activity of the protein kinase. All kinase assays ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2CF9TBB
TBA					More data for this Ligand-Target Pair
Cyclin-A2/Cyclin-dependent kinase 2 (Homo sapiens (Human)-Bos taurus)	BDBM572072 ((R)-N-(4-(3-((7-cyanoquinazolin-2- yl)amino)pyrrol...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description A radiometric protein kinase assay (33PanQinase� Activity Assay) was used for measuring the kinase activity of the protein kinase. All kinase assays ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2CF9TBB
TBA					More data for this Ligand-Target Pair
CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7 (Homo sapiens (Human))	BDBM572072 ((R)-N-(4-(3-((7-cyanoquinazolin-2- yl)amino)pyrrol...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description A radiometric protein kinase assay (33PanQinase� Activity Assay) was used for measuring the kinase activity of the three protein kinases. All kinase ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2CF9TBB
TBA					More data for this Ligand-Target Pair
Cyclin-A2/Cyclin-dependent kinase 2 (Homo sapiens (Human)-Bos taurus)	BDBM572072 ((R)-N-(4-(3-((7-cyanoquinazolin-2- yl)amino)pyrrol...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description A radiometric protein kinase assay (33PanQinase� Activity Assay) was used for measuring the kinase activity of the three protein kinases. All kinase ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2CF9TBB
TBA					More data for this Ligand-Target Pair