BDBM57349 (3-Amino-6-isopropyl-thieno[2,3-b]quinolin-2-yl)-(3,4-dihydro-1H-isoquinolin-2-yl)-methanone::(3-amino-6-isopropyl-thieno[2,3-b]quinolin-2-yl)-(3,4-dihydro-1H-isoquinolin-2-yl)methanone::(3-amino-6-propan-2-yl-2-thieno[2,3-b]quinolinyl)-(3,4-dihydro-1H-isoquinolin-2-yl)methanone::(3-amino-6-propan-2-ylthieno[2,3-b]quinolin-2-yl)-(3,4-dihydro-1H-isoquinolin-2-yl)methanone::(3-azanyl-6-propan-2-yl-thieno[2,3-b]quinolin-2-yl)-(3,4-dihydro-1H-isoquinolin-2-yl)methanone::MLS000556129::SMR000173127::cid_1442685

SMILES: CC(C)c1ccc2nc3sc(C(=O)N4CCc5ccccc5C4)c(N)c3cc2c1

InChI Key: InChIKey=TUDLYWRFLDZAFJ-UHFFFAOYSA-N

Data: 4 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 57349   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
streptokinase A precursor (Streptococcus pyogenes M1 GAS)	BDBM57349 ((3-Amino-6-isopropyl-thieno[2,3-b]quinolin-2-yl)-(...) Show SMILES CC(C)c1ccc2nc3sc(C(=O)N4CCc5ccccc5C4)c(N)c3cc2c1 Show InChI InChI=1S/C24H23N3OS/c1-14(2)16-7-8-20-18(11-16)12-19-21(25)22(29-23(19)26-20)24(28)27-10-9-15-5-3-4-6-17(15)13-27/h3-8,11-12,14H,9-10,13,25H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	1.01E+5	n/a	n/a	n/a	n/a
Broad Institute Curated by PubChem BioAssay					Assay Description Keywords: Group A streptococcus, GAS, streptokinase, expression, virulence, inhibition, dose response, EC50 Assay Overview: The goal of this assa...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2736PBV
					More data for this Ligand-Target Pair
cysteine protease ATG4B isoform a (Homo sapiens (Human))	BDBM57349 ((3-Amino-6-isopropyl-thieno[2,3-b]quinolin-2-yl)-(...) Show SMILES CC(C)c1ccc2nc3sc(C(=O)N4CCc5ccccc5C4)c(N)c3cc2c1 Show InChI InChI=1S/C24H23N3OS/c1-14(2)16-7-8-20-18(11-16)12-19-21(25)22(29-23(19)26-20)24(28)27-10-9-15-5-3-4-6-17(15)13-27/h3-8,11-12,14H,9-10,13,25H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	7.08E+3	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2011) BindingDB Entry DOI: 10.7270/Q2BZ64H1
					More data for this Ligand-Target Pair
sentrin-specific protease 1 (Homo sapiens (Human))	BDBM57349 ((3-Amino-6-isopropyl-thieno[2,3-b]quinolin-2-yl)-(...) Show SMILES CC(C)c1ccc2nc3sc(C(=O)N4CCc5ccccc5C4)c(N)c3cc2c1 Show InChI InChI=1S/C24H23N3OS/c1-14(2)16-7-8-20-18(11-16)12-19-21(25)22(29-23(19)26-20)24(28)27-10-9-15-5-3-4-6-17(15)13-27/h3-8,11-12,14H,9-10,13,25H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	2.58E+3	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay									PubChem Bioassay (2012) BindingDB Entry DOI: 10.7270/Q2MC8XNQ
					More data for this Ligand-Target Pair
sentrin-specific protease 1 (Homo sapiens (Human))	BDBM57349 ((3-Amino-6-isopropyl-thieno[2,3-b]quinolin-2-yl)-(...) Show SMILES CC(C)c1ccc2nc3sc(C(=O)N4CCc5ccccc5C4)c(N)c3cc2c1 Show InChI InChI=1S/C24H23N3OS/c1-14(2)16-7-8-20-18(11-16)12-19-21(25)22(29-23(19)26-20)24(28)27-10-9-15-5-3-4-6-17(15)13-27/h3-8,11-12,14H,9-10,13,25H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	5.22E+3	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay									PubChem Bioassay (2012) BindingDB Entry DOI: 10.7270/Q2R49PCF
					More data for this Ligand-Target Pair
Phospholipase A2 (Homo sapiens (Human))	BDBM57349 ((3-Amino-6-isopropyl-thieno[2,3-b]quinolin-2-yl)-(...) Show SMILES CC(C)c1ccc2nc3sc(C(=O)N4CCc5ccccc5C4)c(N)c3cc2c1 Show InChI InChI=1S/C24H23N3OS/c1-14(2)16-7-8-20-18(11-16)12-19-21(25)22(29-23(19)26-20)24(28)27-10-9-15-5-3-4-6-17(15)13-27/h3-8,11-12,14H,9-10,13,25H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	4.83E+3	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2011) BindingDB Entry DOI: 10.7270/Q26M35BC
					More data for this Ligand-Target Pair