null
SMILES: C[C@H](N(C)c1nc(nc2cnccc12)-c1ccncc1)C(F)(F)F
InChI Key:
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Serine/threonine-protein kinase LATS2 (Homo sapiens (Human)) | BDBM574216 (US11458138, Example 48a) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Human LATS2 kinase domain protein was purchased from Carnabio (catalogue number 01-124), which harbors the catalytic domain of amino acids 553-1088, ... | Citation and Details BindingDB Entry DOI: 10.7270/Q21Z47NH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase LATS1 (Homo sapiens (Human)) | BDBM574216 (US11458138, Example 48a) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The LATS1 biochemical HTRF assay was performed using the HTRF KinEASE-STK S1 kit (CisBio, catalogue number 62ST1PEC) according to manufacturer's ... | Citation and Details BindingDB Entry DOI: 10.7270/Q21Z47NH | |||||||||||
More data for this Ligand-Target Pair |