null
SMILES: CN1CCN(C1=O)c1ccc2CCN(Cc2c1)c1ncc(Cc2ccc(cc2)N2CCOC2=O)s1
InChI Key:
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Neuraminidase (Influenza A virus (strain A/Puerto Rico/8/1934 H1N...) | BDBM575114 (US11459321, Example 57) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.04E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description To assess their antiviral activity, some compounds were tested against murine adapted human influenza (PR8) in vitro. Canine MDCK cells were grown to... | Citation and Details BindingDB Entry DOI: 10.7270/Q2W95DD1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transmembrane anterior posterior transformation protein 1 homolog (Human) | BDBM575114 (US11459321, Example 57) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 742 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description To assess their antiviral activity, some compounds were tested against human cytomegalovirus (HCMV) in vitro. Human MRCS cells were grown to confluen... | Citation and Details BindingDB Entry DOI: 10.7270/Q2W95DD1 | |||||||||||
More data for this Ligand-Target Pair |