BDBM5753 3-(4-Methoxyphenyl)-5-(4-amidopiperizinylacetamido)indeno[1,2-c]pyrazol-4-one::4-({[3-(4-methoxyphenyl)-4-oxo-2H,4H-indeno[1,2-c]pyrazol-5-yl]carbamoyl}methyl)piperazine-1-carboxamide::Indenopyrazole 6n

SMILES: COc1ccc(cc1)-c1n[nH]c2-c3cccc(NC(=O)CN4CCN(CC4)C(N)=O)c3C(=O)c12

InChI Key: InChIKey=BGZVCNSRUXWDPB-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 5753   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-Dependent Kinase 4 (CDK4) (Homo sapiens (Human))	BDBM5753 (3-(4-Methoxyphenyl)-5-(4-amidopiperizinylacetamido...) Show SMILES COc1ccc(cc1)-c1n[nH]c2-c3cccc(NC(=O)CN4CCN(CC4)C(N)=O)c3C(=O)c12 Show InChI InChI=1S/C24H24N6O4/c1-34-15-7-5-14(6-8-15)21-20-22(28-27-21)16-3-2-4-17(19(16)23(20)32)26-18(31)13-29-9-11-30(12-10-29)24(25)33/h2-8H,9-13H2,1H3,(H2,25,33)(H,26,31)(H,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	64	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description The enzyme was assayed with substrate GST-Rb in the presence of 50 uM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...				J Med Chem 45: 5224-32 (2002) Article DOI: 10.1021/jm020171+ BindingDB Entry DOI: 10.7270/Q23J3B5K
					More data for this Ligand-Target Pair
CDK2/CycE (Homo sapiens (Human))	BDBM5753 (3-(4-Methoxyphenyl)-5-(4-amidopiperizinylacetamido...) Show SMILES COc1ccc(cc1)-c1n[nH]c2-c3cccc(NC(=O)CN4CCN(CC4)C(N)=O)c3C(=O)c12 Show InChI InChI=1S/C24H24N6O4/c1-34-15-7-5-14(6-8-15)21-20-22(28-27-21)16-3-2-4-17(19(16)23(20)32)26-18(31)13-29-9-11-30(12-10-29)24(25)33/h2-8H,9-13H2,1H3,(H2,25,33)(H,26,31)(H,27,28)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description The enzyme was assayed with substrate GST-Rb in the presence of 50 uM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...				J Med Chem 45: 5224-32 (2002) Article DOI: 10.1021/jm020171+ BindingDB Entry DOI: 10.7270/Q23J3B5K
					More data for this Ligand-Target Pair