null
SMILES: Cc1cc(ncc1CNCC1(O)CC1)C(=O)Nc1cccc(c1C)-c1cccc(NC(=O)c2cc(C)c(CNCC3(O)CC3)cn2)c1C
InChI Key:
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Programmed cell death 1 ligand/protein 1 (Homo sapiens-Homo sapiens (Human)) | BDBM575499 (N,N'-(2,2'-dimethyl-[1,1'- biphenyl]-3,3'-diyl)bis...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.280 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The effect of compounds and positive compounds of the examples of the present invention on the interaction between PD-1 and PD-L1 was determined by t... | Citation and Details BindingDB Entry DOI: 10.7270/Q23R0X3N | |||||||||||
More data for this Ligand-Target Pair |