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SMILES: COc1cc(ncc1CN1CCC(O)CC1)C(=O)Nc1cccc(c1C)-c1cccc(NC(=O)c2cc(OC)c(CN3CCC(O)CC3)cn2)c1C

InChI Key:

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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 575577   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Programmed cell death 1 ligand/protein 1


(Homo sapiens-Homo sapiens (Human))		BDBM575577
PNG
(N,N'-(2,2'-dimethyl-[1,1'- biphenyl]-3,3'-diyl)bis...)
Show SMILES COc1cc(ncc1CN1CCC(O)CC1)C(=O)Nc1cccc(c1C)-c1cccc(NC(=O)c2cc(OC)c(CN3CCC(O)CC3)cn2)c1C
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 0.330n/an/an/an/an/an/a


TBA

Assay Description
The effect of compounds and positive compounds of the examples of the present invention on the interaction between PD-1 and PD-L1 was determined by t...

Citation and Details

BindingDB Entry DOI: 10.7270/Q23R0X3N
More data for this
Ligand-Target Pair