null
SMILES: C[C@@H]([C@@H]1c2ccc3CCN(Cc3c2)C(=O)C2=Cc3cc(CCCCCCn4nnc5c(C)c1ccc45)ccc3C2C)C(O)=O
InChI Key:
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Kelch-like ECH-associated protein 1/Nuclear factor erythroid 2-related factor 2 (Homo sapiens (Human)) | BDBM576159![]() (WO2022056448, Compound 30) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | WIPO WO2022056448 | n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description In a first step, the Keapl /compound complex was prepared by addition of 100 nL of the compound by ECHO 555, followed by 5 pL aliquots of 2x Keapl. T... | Citation and Details BindingDB Entry DOI: 10.7270/Q21V5J6R | |||||||||||
More data for this Ligand-Target Pair |