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SMILES: Cc1c2ccc3n(CCCCCc4ccc(cc4CC(F)(F)F)C(=O)N4CCc5ccc(cc5C4)[C@@H]2CC(O)=O)nnc13

InChI Key:

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 576170   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Kelch-like ECH-associated protein 1/Nuclear factor erythroid 2-related factor 2


(Homo sapiens (Human))		BDBM576170
PNG
(WO2022056448, Compound 41)
Show SMILES Cc1c2ccc3n(CCCCCc4ccc(cc4CC(F)(F)F)C(=O)N4CCc5ccc(cc5C4)[C@@H]2CC(O)=O)nnc13 |r|
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
WIPO WO2022056448
n/an/a 0.200n/an/an/an/an/an/a


TBA

Assay Description
In a first step, the Keapl /compound complex was prepared by addition of 100 nL of the compound by ECHO 555, followed by 5 pL aliquots of 2x Keapl. T...

Citation and Details

BindingDB Entry DOI: 10.7270/Q21V5J6R
More data for this
Ligand-Target Pair