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SMILES: CCc1ccc(cc1F)-n1c(nc2ccccc2c1=O)-c1cccnc1

InChI Key:

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 576628   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Isoform Tau-F of Microtubule-associated protein tau


(Homo sapiens (Human))		BDBM576628
PNG
(US11472776, Example 17)
Show SMILES CCc1ccc(cc1F)-n1c(nc2ccccc2c1=O)-c1cccnc1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 2.41E+4n/an/an/an/an/an/a


TBA

Assay Description
AlphaLisa Assay (ALA) was used as a primary screen for identifying compounds that inhibit tau oligomer formation. It is a bead based assay that only ...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2ZW1Q5K
More data for this
Ligand-Target Pair