Found 4 hits for monomerid = 577173 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
cAMP-specific 3',5'-cyclic phosphodiesterase 4A [2-825]
(Homo sapiens (Human)) | BDBM577173
![PNG](/data/jpeg/tenK57/BindingDB_577173.png) (10-(4-Chloro-2,5-difluorophenyl)-8-cyclopropyl-3,4...)Show SMILES Fc1cc(-c2c3OCCCc3n3CCN(C4CC4)C(=O)c23)c(F)cc1Cl |(3.02,2.67,;1.51,2.35,;1.04,.89,;-.47,.57,;-.94,-.9,;-2.41,-1.38,;-3.74,-.61,;-5.08,-1.38,;-5.08,-2.92,;-3.74,-3.69,;-2.41,-2.92,;-.94,-3.39,;-.32,-4.8,;1.21,-4.96,;2.12,-3.71,;3.65,-3.87,;4.87,-4.82,;5.08,-3.29,;1.49,-2.31,;2.4,-1.06,;-.04,-2.15,;-1.5,1.71,;-3,1.39,;-1.02,3.17,;.48,3.49,;.96,4.96,)| | PDB MMDB
UniProtKB/SwissProt
GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2XW4P16 |
More data for this Ligand-Target Pair | |
Isoform 3 of cAMP-specific 3',5'-cyclic phosphodiesterase 4D (hPDE4D3) [50-672]
(Homo sapiens (Human)) | BDBM577173
![PNG](/data/jpeg/tenK57/BindingDB_577173.png) (10-(4-Chloro-2,5-difluorophenyl)-8-cyclopropyl-3,4...)Show SMILES Fc1cc(-c2c3OCCCc3n3CCN(C4CC4)C(=O)c23)c(F)cc1Cl |(3.02,2.67,;1.51,2.35,;1.04,.89,;-.47,.57,;-.94,-.9,;-2.41,-1.38,;-3.74,-.61,;-5.08,-1.38,;-5.08,-2.92,;-3.74,-3.69,;-2.41,-2.92,;-.94,-3.39,;-.32,-4.8,;1.21,-4.96,;2.12,-3.71,;3.65,-3.87,;4.87,-4.82,;5.08,-3.29,;1.49,-2.31,;2.4,-1.06,;-.04,-2.15,;-1.5,1.71,;-3,1.39,;-1.02,3.17,;.48,3.49,;.96,4.96,)| | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| | n/a | n/a | 56.2 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2XW4P16 |
More data for this Ligand-Target Pair | |
cAMP-specific 3',5'-cyclic phosphodiesterase 4C [2-712]
() | BDBM577173
![PNG](/data/jpeg/tenK57/BindingDB_577173.png) (10-(4-Chloro-2,5-difluorophenyl)-8-cyclopropyl-3,4...)Show SMILES Fc1cc(-c2c3OCCCc3n3CCN(C4CC4)C(=O)c23)c(F)cc1Cl |(3.02,2.67,;1.51,2.35,;1.04,.89,;-.47,.57,;-.94,-.9,;-2.41,-1.38,;-3.74,-.61,;-5.08,-1.38,;-5.08,-2.92,;-3.74,-3.69,;-2.41,-2.92,;-.94,-3.39,;-.32,-4.8,;1.21,-4.96,;2.12,-3.71,;3.65,-3.87,;4.87,-4.82,;5.08,-3.29,;1.49,-2.31,;2.4,-1.06,;-.04,-2.15,;-1.5,1.71,;-3,1.39,;-1.02,3.17,;.48,3.49,;.96,4.96,)| | PDB MMDB
UniProtKB/SwissProt
GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| | n/a | n/a | 5.94 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2XW4P16 |
More data for this Ligand-Target Pair | |
cAMP-specific 3',5'-cyclic phosphodiesterase 4B [122-736]
(Homo sapiens (Human)) | BDBM577173
![PNG](/data/jpeg/tenK57/BindingDB_577173.png) (10-(4-Chloro-2,5-difluorophenyl)-8-cyclopropyl-3,4...)Show SMILES Fc1cc(-c2c3OCCCc3n3CCN(C4CC4)C(=O)c23)c(F)cc1Cl |(3.02,2.67,;1.51,2.35,;1.04,.89,;-.47,.57,;-.94,-.9,;-2.41,-1.38,;-3.74,-.61,;-5.08,-1.38,;-5.08,-2.92,;-3.74,-3.69,;-2.41,-2.92,;-.94,-3.39,;-.32,-4.8,;1.21,-4.96,;2.12,-3.71,;3.65,-3.87,;4.87,-4.82,;5.08,-3.29,;1.49,-2.31,;2.4,-1.06,;-.04,-2.15,;-1.5,1.71,;-3,1.39,;-1.02,3.17,;.48,3.49,;.96,4.96,)| | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| | n/a | n/a | 0.840 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2XW4P16 |
More data for this Ligand-Target Pair | |