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SMILES: CC(C)Oc1nn(cc1Nc1ncc2cc(C#N)n([C@H]3COC[C@H]3C)c2n1)[C@H](C)C#N

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 577581   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM577581 (2-((1-((S)-1-cyanoethyl)-3-isopropoxy-1H-pyrazol-4...) Show SMILES CC(C)Oc1nn(cc1Nc1ncc2cc(C#N)n([C@H]3COC[C@H]3C)c2n1)[C@H](C)C#N |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022263472	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description LRRK2(human) is incubated with 50 mM HEPES pH 8.0, 0.2 mM EDTA, 0.01 %Brij-35, 1% (w/v) BSA, 5 mM DTT, 250 Mm RLGRDKYKTLRQIRQ, 10 mM Magnesium aceta...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S75KKQ
					More data for this Ligand-Target Pair