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SMILES: CC(=O)N1CC2(C1)CN(C2)c1ccc(CNc2ccc(OCc3ccc(nc3)C(F)(F)F)nn2)c(F)c1

InChI Key:

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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 579850   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Ataxin-1


(Homo sapiens (Human))		BDBM579850
PNG
(US11485727, Example 2.21)
Show SMILES CC(=O)N1CC2(C1)CN(C2)c1ccc(CNc2ccc(OCc3ccc(nc3)C(F)(F)F)nn2)c(F)c1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 2.40n/an/an/an/an/an/a


TBA

Assay Description
5 nM recombinant ATX (Cayman Chemicals) was supplemented to 50 mM Tris buffer (pH 8.0) containing 3 mM KCl, 1 mM CaCl2, 1 mM MgCl2 0.14 mM NaCl, and ...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2X06BXH
More data for this
Ligand-Target Pair