null
SMILES: CCn1c(CO)nn(-c2ccc3c(c2)c(cn(-c2ccccc2Cl)c3=O)C(C)=C)c1=O
InChI Key:
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human)) | BDBM581466 (2-(2-Chlorophenyl)-6-(4-ethyl-3-(hydroxymethyl)-5-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.724 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The following assay is referred to herein as the DHODH Enzymatic Assay. To detect DHODH enzyme activities, dichloroindophenol (DCIP) is added as the ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2WS8Z24 | |||||||||||
More data for this Ligand-Target Pair |