null
SMILES: CC1OC(=O)N[C@@]11C[C@@H](C1)C(=O)N1CCC2(CCC(C2)c2ccc(cc2)C(F)(F)F)CC1
InChI Key:
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Monoglyceride lipase (Homo sapiens (Human)) | BDBM581625 ((rac)-(2s,4s)-8-Methyl-2-(2-(4-(trifluoromethyl)ph...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.230 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,... | Citation and Details BindingDB Entry DOI: 10.7270/Q2S186B3 | |||||||||||
More data for this Ligand-Target Pair |