null
SMILES: CC[C@H](C)[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(N)=O)NC(=O)[C@@H](N)CC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](C(C)C)C(N)=O
InChI Key:
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Corticotropin-releasing factor receptor 2 (Homo sapiens (Human)) | BDBM581978 (DNPSLSIDLTFHLLRTLLELARTQSQRERAEQNRIIFDSV-NH2 (hUcn...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2023285347 | n/a | n/a | 0.120 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Receptor SPA binding assays were performed in white 96-well plates in a total volume of 200 mI per well. Freeze dried analogues were dissolved in 80%... | Citation and Details BindingDB Entry DOI: 10.7270/Q23B63Z2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human)) | BDBM581978 (DNPSLSIDLTFHLLRTLLELARTQSQRERAEQNRIIFDSV-NH2 (hUcn...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2023285347 | n/a | n/a | 0.0700 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Receptor SPA binding assays were performed in white 96-well plates in a total volume of 200 mI per well. Freeze dried analogues were dissolved in 80%... | Citation and Details BindingDB Entry DOI: 10.7270/Q23B63Z2 | |||||||||||
More data for this Ligand-Target Pair |