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SMILES: COc1c(O)c(cc(-c2cn(CC(=O)Nc3cc(nc(F)c3Cl)N3CCOC[C@@H]3C)c3ncn(C)c(=O)c23)c1F)C(N)=O

InChI Key:

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 582398   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
B-cell lymphoma 6 protein


(Homo sapiens)		BDBM582398
PNG
(US11518764, Compound I-411)
Show SMILES COc1c(O)c(cc(-c2cn(CC(=O)Nc3cc(nc(F)c3Cl)N3CCOC[C@@H]3C)c3ncn(C)c(=O)c23)c1F)C(N)=O |r|
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/a 46.2n/an/an/an/an/a


TBA

Assay Description
SPR studies were performed using a Biacore™ T200 instrument (GE Health Sciences Inc.). The BCL6 BTB protein used in the FP assay was biotinylate...

Citation and Details

BindingDB Entry DOI: 10.7270/Q22B92WK
More data for this
Ligand-Target Pair