null
SMILES: OC[C@H](C[C@@H](Cc1ccc(cc1)-c1ccccc1)NC(=O)CC(O)=O)C(O)=O
InChI Key:
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Neprilysin (Homo sapiens (Human)) | BDBM582843 (US11547687, Comparative Compound F | US20230285340...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | 6.31 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details BindingDB Entry DOI: 10.7270/Q2PR8136 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neprilysin/Angiotensin-converting enzyme (Homo sapiens (Human)) | BDBM582843 (US11547687, Comparative Compound F | US20230285340...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 6.31 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The assays were performed in 384-well white opaque plates at 37° C. using the fluorogenic peptide substrates at a concentration of 10 μM in Assa... | Citation and Details BindingDB Entry DOI: 10.7270/Q2BG2STK | |||||||||||
More data for this Ligand-Target Pair |