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SMILES: CCCCNC(=O)Nc1ccc(cc1)N(C)c1ccnc(Nc2cccc(CS(C)(=O)=O)c2)n1

InChI Key: InChIKey=CCGBGVNOJXOFAR-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 5838   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))		BDBM5838
PNG
(3-butyl-1-{4-[(2-{[3-(methanesulfonylmethyl)phenyl...)
Show SMILES CCCCNC(=O)Nc1ccc(cc1)N(C)c1ccnc(Nc2cccc(CS(C)(=O)=O)c2)n1
Show InChI InChI=1S/C24H30N6O3S/c1-4-5-14-26-24(31)28-19-9-11-21(12-10-19)30(2)22-13-15-25-23(29-22)27-20-8-6-7-18(16-20)17-34(3,32)33/h6-13,15-16H,4-5,14,17H2,1-3H3,(H,25,27,29)(H2,26,28,31)
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Article
PubMed
n/an/a 29n/an/an/an/a7.522



GlaxoSmithKline



Assay Description
The assay was using baculovirus-expressed recombinant protein kinase purified as the intracellular domain fused by GST tag, interacting with biotinyl...

Bioorg Med Chem Lett 15: 3519-23 (2005)


Article DOI: 10.1016/j.bmcl.2005.05.096
BindingDB Entry DOI: 10.7270/Q2KK990W
More data for this
Ligand-Target Pair