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SMILES: Cc1cc(=O)c2c(cnc(Cl)c2n1-c1c(Cl)cccc1Cl)N1C[C@@H](O)C[C@@H]1CO

InChI Key:

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 585710   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
G protein-activated inward rectifier potassium channel 1/4


(Homo sapiens (Human))		BDBM585710
PNG
(8-chloro-1-(2,6-dichlorophenyl)-5- ((2R,4S)-4-hydr...)
Show SMILES Cc1cc(=O)c2c(cnc(Cl)c2n1-c1c(Cl)cccc1Cl)N1C[C@@H](O)C[C@@H]1CO |r,wU:23.26,wD:26.30,(4.62,1.32,;3.29,.55,;3.29,-.99,;1.96,-1.76,;1.96,-3.3,;.62,-.99,;-.71,-1.76,;-2.04,-.99,;-2.04,.55,;-.71,1.32,;-.71,2.86,;.62,.55,;1.96,1.32,;1.96,3.92,;.62,4.69,;-.71,3.92,;.62,6.23,;1.96,7,;3.29,6.23,;3.29,4.69,;4.62,3.92,;-.71,-3.3,;.54,-4.2,;.06,-5.67,;.83,-7,;-1.48,-5.67,;-1.96,-4.2,;-3.29,-3.43,;-4.62,-4.2,)|
PDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
US Patent
n/an/a 100n/an/an/an/an/an/a


TBA

Assay Description
Quattro is controlled using IonWorks v2 software to perform the following steps:a. Add 3.5 ul cells plus 3.5 ul external buffer to wells of Quattro P...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2K64NXF
More data for this
Ligand-Target Pair