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SMILES: Cc1cc(=O)c2c(N[C@@H]3COC[C@H]3O)ncc(Cl)c2n1-c1c(Cl)cc(cc1Cl)C#N

InChI Key:

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 585722   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
G protein-activated inward rectifier potassium channel 1/4


(Homo sapiens (Human))		BDBM585722
PNG
(3,5-dichloro-4-(8-chloro-5- (((3R,4S)-4- hydroxyte...)
Show SMILES Cc1cc(=O)c2c(N[C@@H]3COC[C@H]3O)ncc(Cl)c2n1-c1c(Cl)cc(cc1Cl)C#N |r,wU:8.7,wD:12.13,(4.52,-.47,;3.19,-1.24,;3.19,-2.78,;1.85,-3.55,;1.85,-5.09,;.52,-2.78,;-.82,-3.55,;-.82,-5.09,;-2.15,-5.86,;-3.61,-5.38,;-4.52,-6.63,;-3.61,-7.87,;-2.15,-7.4,;-.82,-8.17,;-2.15,-2.78,;-2.15,-1.24,;-.82,-.47,;-.82,1.07,;.52,-1.24,;1.85,-.47,;1.85,2.01,;3.19,2.78,;4.52,2.01,;3.19,4.32,;1.85,5.14,;.52,4.32,;.52,2.78,;-.82,2.01,;1.85,6.68,;1.85,8.22,)|
PDB

UniProtKB/SwissProt

antibodypedia
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GoogleScholar
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PC cid
PC sid
UniChem
US Patent
n/an/a 26n/an/an/an/an/an/a


TBA

Assay Description
Quattro is controlled using IonWorks v2 software to perform the following steps:a. Add 3.5 ul cells plus 3.5 ul external buffer to wells of Quattro P...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2K64NXF
More data for this
Ligand-Target Pair