null

SMILES: CCCCCCCCCCCCCCCC(=O)N[C@@H](CCC(=O)NCCOCCOCC(=O)NCCOCCOCC(=O)NCc1cccc(C[C@@H]2NC(=O)[C@@H](C)NC(=O)[C@H](CCCCN)NC(=O)CCSCc3cccc(CSC[C@H](NC(=O)[C@]4(C)CCCN4C(=O)[C@H](Cc4ccc(O)cc4)NC(=O)[C@H](Cc4cnc[nH]4)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc4c[nH]c5ccc(F)cc45)NC2=O)C(N)=O)c3)c1)C(O)=O

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 586457   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proprotein convertase subtilisin/kexin type 9/Low-density lipoprotein receptor (Homo sapiens (Human))	BDBM586457 (US11530244, Compound 454 | US11530244, Compound 47...) Show SMILES CCCCCCCCCCCCCCCC(=O)N[C@@H](CCC(=O)NCCOCCOCC(=O)NCCOCCOCC(=O)NCc1cccc(C[C@@H]2NC(=O)[C@@H](C)NC(=O)[C@H](CCCCN)NC(=O)CCSCc3cccc(CSC[C@H](NC(=O)[C@]4(C)CCCN4C(=O)[C@H](Cc4ccc(O)cc4)NC(=O)[C@H](Cc4cnc[nH]4)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc4c[nH]c5ccc(F)cc45)NC2=O)C(N)=O)c3)c1)C(O)=O |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The PCSK9 Alexa FRET Standard assay measured the interaction between PCSK9 and an AlexaFluor647 (AF) tagged cyclic peptide, Reagent A (KD=83 nM). A s...				Citation and Details BindingDB Entry DOI: 10.7270/Q2SQ9476
					More data for this Ligand-Target Pair
Proprotein convertase subtilisin/kexin type 9/Low-density lipoprotein receptor (Homo sapiens (Human))	BDBM586457 (US11530244, Compound 454 | US11530244, Compound 47...) Show SMILES CCCCCCCCCCCCCCCC(=O)N[C@@H](CCC(=O)NCCOCCOCC(=O)NCCOCCOCC(=O)NCc1cccc(C[C@@H]2NC(=O)[C@@H](C)NC(=O)[C@H](CCCCN)NC(=O)CCSCc3cccc(CSC[C@H](NC(=O)[C@]4(C)CCCN4C(=O)[C@H](Cc4ccc(O)cc4)NC(=O)[C@H](Cc4cnc[nH]4)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc4c[nH]c5ccc(F)cc45)NC2=O)C(N)=O)c3)c1)C(O)=O |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The PCSK9 Alexa FRET Plus assay measured the interaction between PCSK9 and an AlexaFluor647 (AF) tagged cyclic peptide, Reagent B (KD=35 nM). A solut...				Citation and Details BindingDB Entry DOI: 10.7270/Q2SQ9476
					More data for this Ligand-Target Pair
Proprotein convertase subtilisin/kexin type 9/Low-density lipoprotein receptor (Homo sapiens (Human))	BDBM586457 (US11530244, Compound 454 | US11530244, Compound 47...) Show SMILES CCCCCCCCCCCCCCCC(=O)N[C@@H](CCC(=O)NCCOCCOCC(=O)NCCOCCOCC(=O)NCc1cccc(C[C@@H]2NC(=O)[C@@H](C)NC(=O)[C@H](CCCCN)NC(=O)CCSCc3cccc(CSC[C@H](NC(=O)[C@]4(C)CCCN4C(=O)[C@H](Cc4ccc(O)cc4)NC(=O)[C@H](Cc4cnc[nH]4)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc4c[nH]c5ccc(F)cc45)NC2=O)C(N)=O)c3)c1)C(O)=O |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The PCSK9 Alexa FRET Plus assay measured the interaction between PCSK9 and an AlexaFluor647 (AF) tagged cyclic peptide, Reagent B (KD=35 nM). A solut...				Citation and Details BindingDB Entry DOI: 10.7270/Q2SQ9476
					More data for this Ligand-Target Pair
Proprotein convertase subtilisin/kexin type 9/Low-density lipoprotein receptor (Homo sapiens (Human))	BDBM586457 (US11530244, Compound 454 | US11530244, Compound 47...) Show SMILES CCCCCCCCCCCCCCCC(=O)N[C@@H](CCC(=O)NCCOCCOCC(=O)NCCOCCOCC(=O)NCc1cccc(C[C@@H]2NC(=O)[C@@H](C)NC(=O)[C@H](CCCCN)NC(=O)CCSCc3cccc(CSC[C@H](NC(=O)[C@]4(C)CCCN4C(=O)[C@H](Cc4ccc(O)cc4)NC(=O)[C@H](Cc4cnc[nH]4)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc4c[nH]c5ccc(F)cc45)NC2=O)C(N)=O)c3)c1)C(O)=O |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The PCSK9 Alexa FRET Standard assay measured the interaction between PCSK9 and an AlexaFluor647 (AF) tagged cyclic peptide, Reagent A (KD=83 nM). A s...				Citation and Details BindingDB Entry DOI: 10.7270/Q2SQ9476
					More data for this Ligand-Target Pair