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SMILES: ONC(=O)c1cccc2CN(Cc12)c1nc2cc(c(cc2[nH]1)-c1ccccc1)C(F)(F)F

InChI Key:

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 587621   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histone deacetylase 11


(Homo sapiens (Human))		BDBM587621
PNG
(N-hydroxy-2-(6-phenyl-5- (trifluoromethyl)-1H-benz...)
Show SMILES ONC(=O)c1cccc2CN(Cc12)c1nc2cc(c(cc2[nH]1)-c1ccccc1)C(F)(F)F
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n/an/a<500n/an/an/an/an/an/a


TBA

Assay Description
The probe binding HDAC11 assay was performed using a time resolved fluorescence (TRF) assay format. Recombinant N-terminal GST tag full-length human ...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2M330NW
More data for this
Ligand-Target Pair