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SMILES: Cc1c(C(=O)CN2C3CCC2CC(O)C3)c2ccc(CCS(=O)(=O)C3CC3)cc2n1-c1ccc(Cl)cc1

InChI Key:

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 590213   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Ubiquitin carboxyl-terminal hydrolase 14


(Homo sapiens (Human))
BDBM590213
PNG
(US11560385, Compound 23A | US11560385, Compound 24...)
Show SMILES Cc1c(C(=O)CN2C3CCC2CC(O)C3)c2ccc(CCS(=O)(=O)C3CC3)cc2n1-c1ccc(Cl)cc1 |THB:13:12:8.9:6|
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 75n/an/an/an/an/an/a


TBA

Assay Description
Usp14 Inhibition Assay was described in B. H. Lee et al. Nature 2010, 467 (9), 179.


Citation and Details

BindingDB Entry DOI: 10.7270/Q2445RDM
More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 14


(Homo sapiens (Human))
BDBM590213
PNG
(US11560385, Compound 23A | US11560385, Compound 24...)
Show SMILES Cc1c(C(=O)CN2C3CCC2CC(O)C3)c2ccc(CCS(=O)(=O)C3CC3)cc2n1-c1ccc(Cl)cc1 |THB:13:12:8.9:6|
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a


TBA

Assay Description
Usp14 Inhibition Assay was described in B. H. Lee et al. Nature 2010, 467 (9), 179.


Citation and Details

BindingDB Entry DOI: 10.7270/Q2445RDM
More data for this
Ligand-Target Pair