null
SMILES: Cc1nc(Cc2c(Cl)c(C(=O)CN3C4CCC3[C@@H](O)C4)c(C)n2-c2ccc(cc2)C#N)cs1
InChI Key:
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Ubiquitin carboxyl-terminal hydrolase 14 (Homo sapiens (Human)) | BDBM590687![]() (US11560385, Compound 128B) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Usp14 Inhibition Assay was described in B. H. Lee et al. Nature 2010, 467 (9), 179. | Citation and Details BindingDB Entry DOI: 10.7270/Q2445RDM | |||||||||||
More data for this Ligand-Target Pair |