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SMILES: COc1cncc(OCC[C@H](C)N)c1-c1cc(Nc2cnc(cn2)C#N)n[nH]1

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 590726   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM590726 (US11564920, Example 10) Show SMILES COc1cncc(OCC[C@H](C)N)c1-c1cc(Nc2cnc(cn2)C#N)n[nH]1 |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.16E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The test compounds were added to cultured hERG (human Ether-a-go-go Related Gene) gene stably expressing CHO cell line cells to achieve 0.27 to 100 &...				Citation and Details BindingDB Entry DOI: 10.7270/Q20C50P8
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Chk1 (Homo sapiens (Human))	BDBM590726 (US11564920, Example 10) Show SMILES COc1cncc(OCC[C@H](C)N)c1-c1cc(Nc2cnc(cn2)C#N)n[nH]1 |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description IMAP TR-FRET Screening Express Kit (R8160) was obtained from Molecular Devices. CHK1 kinase (02-117, Carna Bio), FAM-labeled CHK1tide (R7185, Molecul...				Citation and Details BindingDB Entry DOI: 10.7270/Q20C50P8
					More data for this Ligand-Target Pair