null
SMILES: C[C@H]1[C@H]([C@@H]1c1cnn(C)c1)C(=O)Nc1cc2cc(c(F)c(N)c2cn1)-c1cnc2OCCNc2c1C
InChI Key:
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Mitogen-activated protein kinase kinase kinase kinase 1 (Homo sapiens (Human)) | BDBM591145 (US11566003, Compound 34) | PDB NCI pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.0250 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description To a 384 well Proxiplate with 80 nL compound or DMSO spotted on was added 4 μl/well kinase mix. The mixture was preincubated for 30 minutes and ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2GF0ZFV | |||||||||||
More data for this Ligand-Target Pair |