null

SMILES: CNC(=O)c1cncc(c1)-c1cnn2cc(-c3cnn(C)c3)c(OC3CCOC3)nc12

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 592064   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM592064 (US11566028, Example 3) Show SMILES CNC(=O)c1cncc(c1)-c1cnn2cc(-c3cnn(C)c3)c(OC3CCOC3)nc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The inhibitor potency of the exemplified compounds was determined in an enzyme discontinuous assay that measures peptide phosphorylation using FRET m...				Citation and Details BindingDB Entry DOI: 10.7270/Q2ZC86TC
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM592064 (US11566028, Example 3) Show SMILES CNC(=O)c1cncc(c1)-c1cnn2cc(-c3cnn(C)c3)c(OC3CCOC3)nc12 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	115	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2ZC86TC
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 2 (Homo sapiens (Human))	BDBM592064 (US11566028, Example 3) Show SMILES CNC(=O)c1cncc(c1)-c1cnn2cc(-c3cnn(C)c3)c(OC3CCOC3)nc12 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2ZC86TC
					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Homo sapiens (Human))	BDBM592064 (US11566028, Example 3) Show SMILES CNC(=O)c1cncc(c1)-c1cnn2cc(-c3cnn(C)c3)c(OC3CCOC3)nc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01366 BindingDB Entry DOI: 10.7270/Q2PG1WPR
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM592064 (US11566028, Example 3) Show SMILES CNC(=O)c1cncc(c1)-c1cnn2cc(-c3cnn(C)c3)c(OC3CCOC3)nc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01366 BindingDB Entry DOI: 10.7270/Q2PG1WPR
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Mus musculus)	BDBM592064 (US11566028, Example 3) Show SMILES CNC(=O)c1cncc(c1)-c1cnn2cc(-c3cnn(C)c3)c(OC3CCOC3)nc12 Show InChI	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01366 BindingDB Entry DOI: 10.7270/Q2PG1WPR
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 4 (Homo sapiens (Human))	BDBM592064 (US11566028, Example 3) Show SMILES CNC(=O)c1cncc(c1)-c1cnn2cc(-c3cnn(C)c3)c(OC3CCOC3)nc12 Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>200	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2ZC86TC
					More data for this Ligand-Target Pair