null
SMILES: Cc1c(OCCCN2CC[C@@H](O)C2)cccc1-c1cccc2C(CCc12)Oc1cc(OCc2cncc(c2)C#N)c(CN[C@@H](CCO)C(O)=O)cc1Cl
InChI Key:
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Programmed cell death 1 ligand/protein 1 (Homo sapiens-Homo sapiens (Human)) | BDBM592992![]() (US11578054, Example 1015) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.90 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The interaction of PD-1 and PD-L1 can be assessed using soluble, purified preparations of the extracellular domains of the two proteins. The PD-1 and... | Citation and Details BindingDB Entry DOI: 10.7270/Q28P64FR | |||||||||||
More data for this Ligand-Target Pair |