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SMILES: OCC[C@@H](NCc1cc(Cl)c(OC2CCc3c2cccc3-c2cccc(OCCCNC[C@H](O)CO)c2Cl)cc1OCc1cncc(c1)C#N)C(O)=O

InChI Key:

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 593000   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Programmed cell death 1 ligand/protein 1


(Homo sapiens-Homo sapiens (Human))		BDBM593000
PNG
(US11578054, Example 1021)
Show SMILES OCC[C@@H](NCc1cc(Cl)c(OC2CCc3c2cccc3-c2cccc(OCCCNC[C@H](O)CO)c2Cl)cc1OCc1cncc(c1)C#N)C(O)=O |r|
PDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
US Patent
n/an/a 1n/an/an/an/an/an/a


TBA

Assay Description
The interaction of PD-1 and PD-L1 can be assessed using soluble, purified preparations of the extracellular domains of the two proteins. The PD-1 and...

Citation and Details

BindingDB Entry DOI: 10.7270/Q28P64FR
More data for this
Ligand-Target Pair