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SMILES: CCC(N1C[C@H](C)N(C[C@H]1CC)c1nc(=O)n(C)c2ccc(nc12)C#N)c1ccc(Br)cc1

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 594514   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Diacylglycerol kinase alpha [9-727] (Homo sapiens)	BDBM594514 (US11584747, Example 321 | US11584747, Example 322) Show SMILES CCC(N1C[C@H](C)N(C[C@H]1CC)c1nc(=O)n(C)c2ccc(nc12)C#N)c1ccc(Br)cc1 |r| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The reactions were carried out in 50 mM MOPS pH 7.5, 100 mM NaCl, 10 mM MgCl2, 1 μM CaCl2, and 1 mM DTT (assay buffer). The reactions using a de...				Citation and Details BindingDB Entry DOI: 10.7270/Q2Z89HB5
					More data for this Ligand-Target Pair
Diacylglycerol kinase zeta (Homo sapiens)	BDBM594514 (US11584747, Example 321 | US11584747, Example 322) Show SMILES CCC(N1C[C@H](C)N(C[C@H]1CC)c1nc(=O)n(C)c2ccc(nc12)C#N)c1ccc(Br)cc1 |r| Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	760	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The reactions were carried out in 50 mM MOPS pH 7.5, 100 mM NaCl, 10 mM MgCl2, 1 μM CaCl2, and 1 mM DTT (assay buffer). The reactions using a de...				Citation and Details BindingDB Entry DOI: 10.7270/Q2Z89HB5
					More data for this Ligand-Target Pair
Diacylglycerol kinase alpha [9-727] (Homo sapiens)	BDBM594514 (US11584747, Example 321 | US11584747, Example 322) Show SMILES CCC(N1C[C@H](C)N(C[C@H]1CC)c1nc(=O)n(C)c2ccc(nc12)C#N)c1ccc(Br)cc1 |r| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The reactions were carried out in 50 mM MOPS pH 7.5, 100 mM NaCl, 10 mM MgCl2, 1 μM CaCl2, and 1 mM DTT (assay buffer). The reactions using a de...				Citation and Details BindingDB Entry DOI: 10.7270/Q2Z89HB5
					More data for this Ligand-Target Pair
Diacylglycerol kinase zeta (Homo sapiens)	BDBM594514 (US11584747, Example 321 | US11584747, Example 322) Show SMILES CCC(N1C[C@H](C)N(C[C@H]1CC)c1nc(=O)n(C)c2ccc(nc12)C#N)c1ccc(Br)cc1 |r| Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	38	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The reactions were carried out in 50 mM MOPS pH 7.5, 100 mM NaCl, 10 mM MgCl2, 1 μM CaCl2, and 1 mM DTT (assay buffer). The reactions using a de...				Citation and Details BindingDB Entry DOI: 10.7270/Q2Z89HB5
					More data for this Ligand-Target Pair