null

SMILES: CCNC(=O)c1cc2c(cn(C)c(=O)c2s1)-c1cc(NS(=O)(=O)CC)ccc1Oc1c(C)cccc1C

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 594896   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM594896 (US11584756, Compound 147 | US11584756, Example S-1...) Show SMILES CCNC(=O)c1cc2c(cn(C)c(=O)c2s1)-c1cc(NS(=O)(=O)CC)ccc1Oc1c(C)cccc1C Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The bromodomain binding assays were performed by Reaction Biology Corp., Malvern, Pa., USA (www.reactionbiology.com). The BET binding assays were con...				Citation and Details BindingDB Entry DOI: 10.7270/Q2K0786J
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM594896 (US11584756, Compound 147 | US11584756, Example S-1...) Show SMILES CCNC(=O)c1cc2c(cn(C)c(=O)c2s1)-c1cc(NS(=O)(=O)CC)ccc1Oc1c(C)cccc1C Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	299	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The bromodomain binding assays were performed by Reaction Biology Corp., Malvern, Pa., USA (www.reactionbiology.com). The BET binding assays were con...				Citation and Details BindingDB Entry DOI: 10.7270/Q2K0786J
					More data for this Ligand-Target Pair