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SMILES: CN1c2nc(ccc2CC[C@H](NC(=O)c2cc(Oc3ccccc3)ccn2)C1=O)C#CC(C)(N)C(F)(F)F

InChI Key:

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 594974   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Receptor-interacting serine/threonine-protein kinase 1


(Homo sapiens (Human))		BDBM594974
PNG
(US11584758, Compound I-60)
Show SMILES CN1c2nc(ccc2CC[C@H](NC(=O)c2cc(Oc3ccccc3)ccn2)C1=O)C#CC(C)(N)C(F)(F)F |r|
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 8.5n/an/an/an/an/an/a


TBA

Assay Description
In this example, compounds of the disclosure were evaluated using a biochemical assay using the ADP-Glo™ technology. ADP-Glo™ (Promega, Madison, Wis....

Citation and Details

BindingDB Entry DOI: 10.7270/Q2FB56VP
More data for this
Ligand-Target Pair