null

SMILES: CC(C)(C)[C@@H](N)C(=O)N1CC[C@H]1C(=O)NCc1ccc(cc1)C(N)=N

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 594978   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
thrombin (Homo sapiens (Human))	BDBM594978 (US11584714, Compound 1005) Show SMILES CC(C)(C)[C@@H](N)C(=O)N1CC[C@H]1C(=O)NCc1ccc(cc1)C(N)=N |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The thrombin assay utilizes a fluorogenic peptide substrate (Boc-VPR-AMC (R&D Systems) and was run at room temperature in an assay buffer containing ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2VH5SRT
					More data for this Ligand-Target Pair
Mannan-binding lectin serine protease 2 (Homo sapiens)	BDBM594978 (US11584714, Compound 1005) Show SMILES CC(C)(C)[C@@H](N)C(=O)N1CC[C@H]1C(=O)NCc1ccc(cc1)C(N)=N |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	6.25E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay was run at room temperature in an assay buffer containing 20 mM Hepes, pH 7.4, 140 mM NaCl and 0.1% Tween 20. Assay parameters were adjuste...				Citation and Details BindingDB Entry DOI: 10.7270/Q2VH5SRT
					More data for this Ligand-Target Pair