null
SMILES: COc1cc(CC[C@@H](N)C(=O)N[C@@H](C)C(=O)NCc2ccc(cc2)C(N)=N)cc(OC)c1
InChI Key:
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
thrombin (Homo sapiens (Human)) | BDBM595084 (US11584714, Compound 1112) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | <500 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The thrombin assay utilizes a fluorogenic peptide substrate (Boc-VPR-AMC (R&D Systems) and was run at room temperature in an assay buffer containing ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2VH5SRT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mannan-binding lectin serine protease 2 (Homo sapiens) | BDBM595084 (US11584714, Compound 1112) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | <500 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The assay was run at room temperature in an assay buffer containing 20 mM Hepes, pH 7.4, 140 mM NaCl and 0.1% Tween 20. Assay parameters were adjuste... | Citation and Details BindingDB Entry DOI: 10.7270/Q2VH5SRT | |||||||||||
More data for this Ligand-Target Pair |