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SMILES: CC(C)C(=O)N1CCC(CC1)c1cc(c([nH]1)C(\N)=N/C=N)-c1ccc(NC(=O)c2cn(C(C)C)c(=O)n(C3CCCCC3)c2=O)cc1

InChI Key:

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 596414   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosine-protein kinase receptor UFO


(Homo sapiens (Human))
BDBM596414
PNG
(US11591338, Example 90)
Show SMILES CC(C)C(=O)N1CCC(CC1)c1cc(c([nH]1)C(\N)=N/C=N)-c1ccc(NC(=O)c2cn(C(C)C)c(=O)n(C3CCCCC3)c2=O)cc1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 55n/an/an/an/an/an/a


TBA

Assay Description
The kinase assay buffer contained 50 mM HEPES, pH7.5, 10 mM MgCl2, 1 mM EGTA, 0.01% NP-40 and 2 mM DTT. 0.1 ul test compounds dissolved in DMSO were ...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2MW2N2P
More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3


(Homo sapiens (Human))
BDBM596414
PNG
(US11591338, Example 90)
Show SMILES CC(C)C(=O)N1CCC(CC1)c1cc(c([nH]1)C(\N)=N/C=N)-c1ccc(NC(=O)c2cn(C(C)C)c(=O)n(C3CCCCC3)c2=O)cc1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<5n/an/an/an/an/an/a


TBA

Assay Description
The kinase assay buffer contained 50 mM HEPES, pH7.5, 10 mM MgCl2, 1 mM EGTA, 0.01% NP-40 and 2 mM DTT. 0.1 ul test compounds dissolved in DMSO were ...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2MW2N2P
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Mer


(Homo sapiens (Human))
BDBM596414
PNG
(US11591338, Example 90)
Show SMILES CC(C)C(=O)N1CCC(CC1)c1cc(c([nH]1)C(\N)=N/C=N)-c1ccc(NC(=O)c2cn(C(C)C)c(=O)n(C3CCCCC3)c2=O)cc1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 7.5n/an/an/an/an/an/a


TBA

Assay Description
The kinase assay buffer contained 50 mM HEPES, pH7.5, 10 mM MgCl2, 1 mM EGTA, 0.01% NP-40 and 2 mM DTT. 0.1 ul test compounds dissolved in DMSO were ...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2MW2N2P
More data for this
Ligand-Target Pair