BDBM60590 6-(1-{6-phenyl-[1,2,4]triazolo[4,3-b][1,2,4]triazin-3-yl}cyclopropyl)quinoline (5)

SMILES: C1CC1(c1nnc2ncc(nn12)-c1ccccc1)c1ccc2ncccc2c1

InChI Key: InChIKey=SRSRMWXJQNEQGS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 60590   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine kinase receptor c-Met (c-Met) (Homo sapiens (Human))	BDBM60590 (6-(1-{6-phenyl-[1,2,4]triazolo[4,3-b][1,2,4]triazi...) Show SMILES C1CC1(c1nnc2ncc(nn12)-c1ccccc1)c1ccc2ncccc2c1 Show InChI InChI=1S/C22H16N6/c1-2-5-15(6-3-1)19-14-24-21-26-25-20(28(21)27-19)22(10-11-22)17-8-9-18-16(13-17)7-4-12-23-18/h1-9,12-14H,10-11H2	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	7.0	25
Tianjin University of Science and Technology					Assay Description The c-Met kinase activity of five target compounds and three positive compounds were evaluated using standard Z-LYTE Assays (fluorescence resonance e...				Bioorg Chem 65: 146-58 (2016) Article DOI: 10.1016/j.bioorg.2016.02.009 BindingDB Entry DOI: 10.7270/Q2VT1QVX
					More data for this Ligand-Target Pair