BDBM60597 (E)-N-(1,3-benzothiazol-2-yl)-2-cyano-3-(6-hydroxy-4-keto-chromen-3-yl)acrylamide::(E)-N-(1,3-benzothiazol-2-yl)-2-cyano-3-(6-hydroxy-4-oxo-1-benzopyran-3-yl)-2-propenamide::(E)-N-(1,3-benzothiazol-2-yl)-2-cyano-3-(6-hydroxy-4-oxochromen-3-yl)prop-2-enamide::(E)-N-(1,3-benzothiazol-2-yl)-2-cyano-3-(6-oxidanyl-4-oxidanylidene-chromen-3-yl)prop-2-enamide::(E)-N-Benzothiazol-2-yl-2-cyano-3-(6-hydroxy-4-oxo-4H-chromen-3-yl)-acrylamide::MLS000332015::SMR000221475::cid_1839490

SMILES: Oc1ccc2occ(\C=C(/C#N)C(=O)Nc3nc4ccccc4s3)c(=O)c2c1

InChI Key: InChIKey=GADKWXHYPZMQRZ-YRNVUSSQSA-N

Data: 4 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 60597   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Intestinal alkaline phosphatase (Homo sapiens (Human))	BDBM60597 ((E)-N-(1,3-benzothiazol-2-yl)-2-cyano-3-(6-hydroxy...) Show SMILES Oc1ccc2occ(\C=C(/C#N)C(=O)Nc3nc4ccccc4s3)c(=O)c2c1 Show InChI InChI=1S/C20H11N3O4S/c21-9-11(19(26)23-20-22-15-3-1-2-4-17(15)28-20)7-12-10-27-16-6-5-13(24)8-14(16)18(12)25/h1-8,10,24H,(H,22,23,26)/b11-7+	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	PCBioAssay	n/a	n/a	n/a	n/a	8.15E+4	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q29G5K8R
					More data for this Ligand-Target Pair
Alpi (Rattus norvegicus (Rat))	BDBM60597 ((E)-N-(1,3-benzothiazol-2-yl)-2-cyano-3-(6-hydroxy...) Show SMILES Oc1ccc2occ(\C=C(/C#N)C(=O)Nc3nc4ccccc4s3)c(=O)c2c1 Show InChI InChI=1S/C20H11N3O4S/c21-9-11(19(26)23-20-22-15-3-1-2-4-17(15)28-20)7-12-10-27-16-6-5-13(24)8-14(16)18(12)25/h1-8,10,24H,(H,22,23,26)/b11-7+	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	PCBioAssay	n/a	n/a	n/a	n/a	8.50E+4	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2J38R0R
					More data for this Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme (Homo sapiens (Human))	BDBM60597 ((E)-N-(1,3-benzothiazol-2-yl)-2-cyano-3-(6-hydroxy...) Show SMILES Oc1ccc2occ(\C=C(/C#N)C(=O)Nc3nc4ccccc4s3)c(=O)c2c1 Show InChI InChI=1S/C20H11N3O4S/c21-9-11(19(26)23-20-22-15-3-1-2-4-17(15)28-20)7-12-10-27-16-6-5-13(24)8-14(16)18(12)25/h1-8,10,24H,(H,22,23,26)/b11-7+	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	PCBioAssay	n/a	n/a	n/a	n/a	8.85E+4	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2J101NV
					More data for this Ligand-Target Pair
Alkaline phosphatase placental-like (Homo sapiens (Human))	BDBM60597 ((E)-N-(1,3-benzothiazol-2-yl)-2-cyano-3-(6-hydroxy...) Show SMILES Oc1ccc2occ(\C=C(/C#N)C(=O)Nc3nc4ccccc4s3)c(=O)c2c1 Show InChI InChI=1S/C20H11N3O4S/c21-9-11(19(26)23-20-22-15-3-1-2-4-17(15)28-20)7-12-10-27-16-6-5-13(24)8-14(16)18(12)25/h1-8,10,24H,(H,22,23,26)/b11-7+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	PCBioAssay	n/a	n/a	n/a	n/a	9.11E+4	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2SJ1J25
					More data for this Ligand-Target Pair